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Image Search Results
Journal: eLife
Article Title: SMAD4 and TGFβ are architects of inverse genetic programs during fate determination of antiviral CTLs
doi: 10.7554/eLife.76457
Figure Lengend Snippet: ( A ) Histograms show CFSE dilution at 3.5 dpi. ( B ) OTI-S4TR2Ctrl (white fill) and OTI-S4TR2KO cells (gray fill) were transferred to C57BL/6 mice before infection with X31-OVA. 5-Bromo-2-deoxyuridine (BrdU) was administered by IP injection 3 hr before sacrifice. Bar graphs show percentages of BrdU + donor cells at 6 dpi and 8 dpi. Data are means ± standard deviation (SD) ( n = 3/group). Two independent experiments gave similar results. p values were calculated using Student’s t tests.
Article Snippet: Alternatively, mice received a single injection of BrdU by i.p. injection at 30 dpi and donor cells were analyzed 3–6 hr later, using
Techniques: Infection, Injection, Standard Deviation
Journal: Cancer Cell International
Article Title: Antiproliferative and apoptotic effects of telmisartan in human glioma cells
doi: 10.1186/s12935-023-02963-1
Figure Lengend Snippet: The effects of telmisartan on the colony formation and proliferation of human LN229, U87MG and LNZ308 glioblastoma cells. A Glioma cells were treated with DMSO or different concentrations of telmisartan for 14 days. The number of colonies is shown as the mean ± SD of 3 independent tests (** p < 0.01; *** p < 0.001). B Glioma cells were treated with telmisartan for 48 h, and then BrdU incorporation by cells was performed using a FITC BrdU Flow Kit. M1, BrdU-negative cells; M2, BrdU-positive cells. Cells untreated with BrdU were used as blanks. The results are representative data from two independent experiments. These results showed telmisartan dose-dependently inhibits colony formation and provokes apoptosis of GBM cells
Article Snippet: We used
Techniques: BrdU Incorporation Assay